Plates-formes PFRN

Accueil > Bibliographie > Total synthesis of mololipids : a new series of anti-HIV Moloka’iamine (...)

Total synthesis of mololipids : a new series of (...)

Bioorg Med Chem Lett. 2000 Dec ;10(23):2679-81
Total synthesis of mololipids : a new series of anti-HIV Moloka’iamine derivatives.
Schoenfeld RC, Lumb JP, Fantini J, Ganem B.

A new family of bioactive bromotyrosine derivatives, termed mololipids, was recently isolated from a Hawaiian sponge, but could not be resolved into individual components by chromatography. To complete their structural characterization and better understand structure-activity relationships, the first pure samples of dimyristoyl, distearoyl, dioleoyl, and stearoyl/oleoyl mololipids have now been prepared by total synthesis, and their anti-HIV activity investigated.


    Ils nous font confiance

  • logo amu
  • logo cnrs
  • logo inserm
  • logo AP-HM
  • logo F�d�ration pour la Recherche sur le Cerveau
  • logo Fondation pour la Recherche Medical en France
  • logo IBiSA
  • logo Europe programme FEDER
  • logo Agence Nationale de la Recherche
  • logo Plateforme Technologique Aix-Marseille
  • logo Vect-Horus
  • logo Neuron Experts