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Purification of thirteen toxins active on mice from the (...)

Toxicon. 1984 ;22(2):279-91.
Purification of thirteen toxins active on mice from the venom of the North African scorpion Buthus occitanus tunetanus.
Martin MF, Rochat H.

A combination of several equilibrium chromatographic steps permitted us to purify thirteen proteins from the venom of Buthus occitanus tunetanus using the mouse as the test animal for lethality measurement. These proteins have been characterized by their amino acid composition and, for seven of them, by their N-terminal or complete amino acid sequence. The structural data obtained correlate well with the pharmacological and antigenic properties of the neurotoxins.

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