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Functional characterization of nonmetastatic (...)

Clin Endocrinol (Oxf). 2013 Aug ;79(2):170-7
Functional characterization of nonmetastatic paraganglioma and pheochromocytoma by (18) F-FDOPA PET : focus on missed lesions.
Gabriel S, Blanchet EM, Sebag F, Chen CC, Fakhry N, Deveze A, Barlier A, Morange I, Pacak K, Taieb D.

To evaluate the clinical value of (18) F-fluorodihydroxyphenylalanine ((18) F-FDOPA) PET in relation to tumour localization and the patient’s genetic status in a large series of pheochromocytoma/paraganglioma (PHEO/PGL) patients and to discuss in detail false-negative results. A retrospective study of PGL patients who were investigated with (18) F-FDOPA PET or PET/CT imaging in two academic endocrine tumour centres was conducted (La Timone University Hospital, Marseilles, France and National Institutes of Health (NIH), Bethesda, MD, USA).


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